Oral Small Molecule Therapeutics
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All Stocks (254)
| Company | Market Cap | Price |
|---|---|---|
|
CRMD
CorMedix Inc.
MINOCIN is an oral small-molecule antibiotic, reflecting an oral antibiotic product line.
|
$857.72M |
$11.40
-0.78%
|
|
DAWN
Day One Biopharmaceuticals, Inc.
Day One Biopharmaceuticals markets and develops Oral Small Molecule Therapeutics (OJEMDA/tovorafenib) as a lead product.
|
$856.33M |
$8.35
-0.18%
|
|
KALV
KalVista Pharmaceuticals, Inc.
EKTERLY (sebetralstat) is KalVista's lead asset and is an oral small-molecule therapeutic for acute hereditary angioedema, directly reflecting their product category.
|
$844.72M |
$16.91
|
|
GOSS
Gossamer Bio, Inc.
Seralutinib is a small molecule therapeutic, classifying under small molecule therapeutics in the existing taxonomy.
|
$818.57M |
$3.75
+4.03%
|
|
ESPR
Esperion Therapeutics, Inc.
Oral small-molecule LDL-C lowering therapies (NEXLETOL/NEXLIZET).
|
$776.25M |
$3.79
-1.43%
|
|
GYRE
Gyre Therapeutics, Inc.
Gyre Therapeutics develops and commercializes small-molecule therapeutics (lead Hydronidone/F351 and multiple pipeline agents, plus licensed products) for fibrotic diseases, which fits the 'Oral Small Molecule Therapeutics' category.
|
$740.65M |
$7.55
-1.82%
|
|
RIGL
Rigel Pharmaceuticals, Inc.
All approved and development-stage oral agents (fostamatinib, olutasidenib, pralsetinib, R289) are delivered orally, aligning with Oral Small Molecule Therapeutics.
|
$731.48M |
$41.90
+2.75%
|
|
CGEM
Cullinan Therapeutics, Inc.
Zipalertinib is an orally administered small-molecule EGFR inhibitor targeting ex20ins NSCLC.
|
$704.17M |
$11.00
-7.72%
|
|
FULC
Fulcrum Therapeutics, Inc.
Fulcrum's lead asset pociredir is an oral small molecule therapeutic intended to induce HbF in SCD.
|
$703.19M |
$12.75
-1.92%
|
|
OMER
Omeros Corporation
Pipeline includes oral small-molecule therapeutics in addition to biologics.
|
$690.77M |
$9.62
-5.22%
|
|
CRVS
Corvus Pharmaceuticals, Inc.
Soquelitinib is an orally bioavailable small molecule therapeutic, classifying the program under Oral Small Molecule Therapeutics.
|
$623.68M |
$8.41
+0.48%
|
|
AQST
Aquestive Therapeutics, Inc.
Anaphylm's oral small-molecule epinephrine film and AQST-108 (epinephrine topical gel) indicate a focus on oral small-molecule therapeutics delivered via film/topical formats.
|
$619.28M |
$5.92
-4.67%
|
|
RAPT
RAPT Therapeutics, Inc.
Tivumecirnon is an oral small-molecule CCR4 antagonist, aligning with Oral Small Molecule Therapeutics.
|
$608.59M |
$34.28
-6.83%
|
|
VSTM
Verastem, Inc.
Lead products are oral small-molecule inhibitors (avutometinib, defactinib) used in combination therapy, fitting the 'Oral Small Molecule Therapeutics' category.
|
$591.45M |
$9.33
-2.91%
|
|
VTYX
Ventyx Biosciences, Inc.
VTX assets are oral small molecule therapeutics for autoimmune/inflammatory diseases (NLRP3 inhibitors).
|
$584.02M |
$8.49
+3.72%
|
|
ANNX
Annexon, Inc.
ANX1502 is an oral small molecule inhibitor, categorized under Oral Small Molecule Therapeutics.
|
$546.14M |
$4.95
-0.50%
|
|
DSGN
Design Therapeutics, Inc.
Company develops small-molecule therapeutics (GeneTAC) targeting inherited nucleotide repeat disorders.
|
$537.02M |
$9.14
-3.08%
|
|
LXRX
Lexicon Pharmaceuticals, Inc.
Lexicon's pipeline includes oral small-molecule therapeutics pilavapadin (LX9211) and LX9851; these are oral small-molecule drugs, a major product category in their portfolio.
|
$472.42M |
$1.25
-3.46%
|
|
ZVRA
Zevra Therapeutics, Inc.
KP1077 and OLPRUVA are oral small molecule therapies (prodrugs); Zevra's pipeline includes oral small-molecule therapeutics.
|
$467.61M |
$8.15
-2.16%
|
|
SIGA
SIGA Technologies, Inc.
TPOXX is available in an oral formulation, placing SIGA in the Oral Small Molecule Therapeutics category.
|
$462.57M |
$6.36
-1.55%
|
|
BIOA
BioAge Labs, Inc.
BioAge's lead program BGE-102 is an oral small-molecule therapeutic, and APJ agonists are being developed for obesity, fitting the 'Oral Small Molecule Therapeutics' investable theme.
|
$461.75M |
$12.59
-2.29%
|
|
MNPR
Monopar Therapeutics Inc.
ALXN1840 is an oral small-molecule therapeutic for Wilson disease, aligning with Oral Small Molecule Therapeutics.
|
$460.31M |
$76.04
+1.92%
|
|
ETON
Eton Pharmaceuticals, Inc.
KHINDIVI (ET-400), ET-600, ET-700, and ET-800 involve oral/ready formulations (e.g., desmopressin, hydrocortisone, zinc) consistent with the Oral Small Molecule Therapeutics category.
|
$447.85M |
$15.89
-4.82%
|
|
AKBA
Akebia Therapeutics, Inc.
Vafseo (vadadustat) is Akebia's core product, an oral small-molecule therapeutic (HIF-PHI) for CKD anemia, aligning with the 'Oral Small Molecule Therapeutics' investable theme.
|
$440.14M |
$1.60
-3.31%
|
|
PRTC
PureTech Health plc
LYT-100 is an oral small-molecule therapeutic for IPF.
|
$436.16M |
$16.78
-0.77%
|
|
ANRO
Alto Neuroscience, Inc.
ALTO-300 is an oral small molecule therapeutic (melatonin receptor agonist/5-HT2C antagonist), a major product category.
|
$409.67M |
$17.34
+14.64%
|
|
GALT
Galectin Therapeutics Inc.
The company is pursuing a small molecule oral galectin-3 inhibitor program via Galectin Sciences LLC, representing an Oral Small Molecule Therapeutics pathway.
|
$400.38M |
$6.54
+4.72%
|
|
ITOS
iTeos Therapeutics, Inc.
EOS-984 ENT1 inhibitor and other small-molecule assets indicate development or use of oral small molecule therapeutics.
|
$388.48M |
$10.15
|
|
DRUG
Bright Minds Biosciences Inc.
Developing small-molecule therapeutics (5-HT receptor agonists), a major drug class.
|
$375.81M |
$85.13
+1.12%
|
|
VIGL
Vigil Neuroscience, Inc.
VG-3927 is an oral small molecule TREM2 agonist, placing Vigil's small-molecule therapeutic program under Oral Small Molecule Therapeutics.
|
$375.71M |
$8.05
|
|
VNDA
Vanda Pharmaceuticals Inc.
Fanapt and other marketed/potential small-molecule therapies (e.g., Tradipitant) are oral small molecule therapeutics.
|
$368.13M |
$6.52
+4.65%
|
|
ACRS
Aclaris Therapeutics, Inc.
ATI-2138 is an oral small-molecule therapeutic (ITK/JAK3 inhibitor), aligning with Oral Small Molecule Therapeutics.
|
$352.08M |
$3.21
-1.38%
|
|
AVXL
Anavex Life Sciences Corp.
Company's lead product and pipeline consist of oral small-molecule therapeutics (ANAVEX 2-73 and ANAVEX 3-71).
|
$345.29M |
$4.02
|
|
MREO
Mereo BioPharma Group plc
Alvelestat is an oral small-molecule therapeutic, aligning with Oral Small Molecule Therapeutics.
|
$345.24M |
$2.21
+1.61%
|
|
NMRA
Neumora Therapeutics, Inc. Common Stock
Navacaprant is an oral small-molecule therapeutic, aligning with Oral Small Molecule Therapeutics.
|
$338.47M |
$1.94
-7.18%
|
|
CTNM
Contineum Therapeutics, Inc. Class A Common Stock
Lead programs are oral small-molecule therapeutics targeting NI&I indications.
|
$326.13M |
$11.59
-0.34%
|
|
ENTA
Enanta Pharmaceuticals, Inc.
Lead RSV programs (zelicapavir and EDP-323) are oral small-molecule therapeutics, aligning with the Oral Small Molecule Therapeutics theme.
|
$314.90M |
$14.65
-0.51%
|
|
ACIU
AC Immune S.A.
Oral Small Molecule Therapeutics – Morphomer platform developing small-molecule inhibitors (e.g., Tau aggregation, alpha-synuclein) for neurodegeneration.
|
$314.50M |
$3.21
+1.90%
|
|
AARD
Aardvark Therapeutics, Inc. Common Stock
ARD-101 and ARD-201 are oral small-molecule therapeutics targeting satiety pathways for metabolic and rare-disease indications.
|
$313.09M |
$14.76
+2.25%
|
|
AMRN
Amarin Corporation plc
Icosapent ethyl is administered orally as a lipid-lowering therapeutic, aligning with the 'Oral Small Molecule Therapeutics' category.
|
$295.34M |
$14.32
-0.28%
|
|
PBYI
Puma Biotechnology, Inc.
Neratinib and alisertib are oral small-molecule therapeutics, indicating a major category of oral oncology drugs.
|
$295.17M |
$5.83
-0.43%
|
|
ASMB
Assembly Biosciences, Inc.
Pipeline products are administered orally, classifying the company under oral small-molecule therapeutics as a core product modality.
|
$276.97M |
$34.77
-3.67%
|
|
ALDX
Aldeyra Therapeutics, Inc.
ADX-629 is an oral RASP modulator, classed as oral small molecule therapeutics.
|
$271.93M |
$4.19
-7.71%
|
|
FHTX
Foghorn Therapeutics Inc.
FHD-909 is a selective oral small-molecule inhibitor; pipeline includes additional oral small-molecule therapeutics.
|
$250.99M |
$4.38
-1.46%
|
|
AVIR
Atea Pharmaceuticals, Inc.
The company is developing an oral fixed-dose combination regimen of bemnifosbuvir and ruzasvir for HCV, aligning with the 'Oral Small Molecule Therapeutics' category.
|
$249.98M |
$3.15
-0.16%
|
|
ACHV
Achieve Life Sciences, Inc.
Cytisinicline is an oral small-molecule therapeutic candidate for smoking cessation, fitting the 'Oral Small Molecule Therapeutics' investable theme.
|
$237.13M |
$4.51
-2.80%
|
|
IVA
Inventiva S.A.
Inventiva's lanifibranor is an orally administered small-molecule therapeutic for MASH, fitting the 'Oral Small Molecule Therapeutics' tag.
|
$234.05M |
$4.44
-0.45%
|
|
IMRX
Immuneering Corporation
Atebimetinib (IMM-1-104) is an oral small-molecule therapeutic in clinical trials.
|
$220.82M |
$5.88
-3.21%
|
|
SLS
SELLAS Life Sciences Group, Inc.
SLS009 (tambiciclib) is a small-molecule CDK9 inhibitor, qualifying as Oral Small Molecule Therapeutics.
|
$213.75M |
$2.08
+2.22%
|
|
SGMT
Sagimet Biosciences Inc.
Sagimet's lead and second FASN inhibitors (denifanstat, TVB-3567) are oral small-molecule therapeutics, directly aligning with this tag.
|
$202.61M |
$6.16
-1.20%
|
|
NVCT
Nuvectis Pharma, Inc.
NXP900 is described with oral dosing (mg/day), supporting the tag 'Oral Small Molecule Therapeutics'.
|
$193.22M |
$7.64
+0.66%
|
|
NTHI
Neonc Technologies Holdings, Inc.
NEO212 is an oral small molecule therapeutic being developed for brain tumors.
|
$189.29M |
$10.02
-1.86%
|
|
DERM
Journey Medical Corporation
Emrosi is an oral small molecule therapeutic (minocycline extended-release) and represents Journey Medical's flagship product launched in 2025.
|
$186.98M |
$7.63
-0.46%
|
|
CCCC
C4 Therapeutics, Inc.
Lead assets (e.g., cemsidomide) are orally bioavailable small-molecule degraders, fitting the 'Oral Small Molecule Therapeutics' category.
|
$175.79M |
$2.46
-0.20%
|
|
TNXP
Tonix Pharmaceuticals Holding Corp.
TNX-102 SL is Tonix's lead oral small-molecule drug for fibromyalgia (cyclobenzaprine HCl sublingual), a direct product the company develops and plans to bring to market.
|
$169.01M |
$18.98
-1.56%
|
|
CRDF
Cardiff Oncology, Inc.
Onvansertib is an oral small-molecule therapeutic, representing the company's primary product modality.
|
$159.00M |
$2.42
+1.46%
|
|
BDTX
Black Diamond Therapeutics, Inc.
BDTX-1535 is a brain-penetrant, fourth-generation EGFR inhibitor, representing an oral small molecule therapeutic.
|
$158.85M |
$2.71
-3.05%
|
|
ACTU
Actuate Therapeutics Inc
Elraglusib includes oral tablet formulation development, aligning with the Oral Small Molecule Therapeutics category.
|
$156.00M |
$7.03
-6.52%
|
|
SAVA
Cassava Sciences, Inc.
Direct product category: simufilam is developed as an oral small-molecule therapeutic.
|
$154.10M |
$3.23
+1.10%
|
|
GANX
Gain Therapeutics, Inc.
GT-02287 is a small-molecule therapeutic candidate, aligning with the major product category of oral small-molecule therapeutics.
|
$148.83M |
$4.01
-3.02%
|
|
IXHL
Incannex Healthcare Limited
Incannex develops oral small-molecule therapeutics as fixed-dose drug combinations (IHL-42X).
|
$147.08M |
$0.39
-6.83%
|
|
TNYA
Tenaya Therapeutics, Inc.
TN-301 is an oral small-molecule HDAC6 inhibitor, qualifying as Oral Small Molecule Therapeutics.
|
$138.53M |
$0.80
-5.87%
|
|
SPRO
Spero Therapeutics, Inc.
Tebipenem HBr is an oral small-molecule antibiotic, which is the lead product and central to Spero’s current business focus.
|
$130.56M |
$2.33
-0.64%
|
|
CGTX
Cognition Therapeutics, Inc.
CT1812 (zervimesine) is an orally delivered small-molecule therapeutic, the core product of the company.
|
$124.17M |
$1.66
-2.07%
|
|
CRBP
Corbus Pharmaceuticals Holdings, Inc.
CRB-913 is an oral small molecule CB1 inverse agonist aimed at obesity; classifies as an oral small molecule therapeutic.
|
$118.88M |
$9.54
-1.70%
|
|
IKT
Inhibikase Therapeutics, Inc.
IKT's lead program IKT-001Pro is an oral small-molecule therapeutic prodrug, fitting the 'Oral Small Molecule Therapeutics' investable theme.
|
$114.76M |
$1.63
+5.84%
|
|
VTVT
vTv Therapeutics Inc.
Cadisegliatin is an oral, small-molecule therapeutic developed by the company for Type 1 Diabetes, directly matching the 'Oral Small Molecule Therapeutics' category.
|
$110.63M |
$34.90
+0.78%
|
|
UNCY
Unicycive Therapeutics, Inc.
Lead programs Oxylanthanum Carbonate (OLC) and UNI-494 are oral small-molecule therapeutics targeting kidney disease and hyperphosphatemia/acute kidney injury.
|
$110.03M |
$5.91
-5.14%
|
|
ATOS
Atossa Therapeutics, Inc.
Z-endoxifen is an oral small-molecule therapeutic, and Atossa is prioritizing its metastatic breast cancer indication, representing a major product category.
|
$106.57M |
$0.72
-12.23%
|
|
ZNTL
Zentalis Pharmaceuticals, Inc.
Azenosertib is an oral small-molecule inhibitor, making this a direct major product category for the company.
|
$100.99M |
$1.41
+0.36%
|
|
PRLD
Prelude Therapeutics Incorporated
Lead programs include oral small-molecule degraders (e.g., SMARCA2 degraders, KAT6A degrader, CDK9 inhibitor), classifying them under Oral Small Molecule Therapeutics.
|
$96.79M |
$1.91
+11.70%
|
|
ANEB
Anebulo Pharmaceuticals, Inc.
Anebulo's lead candidate selonabant is a small molecule therapeutic (initially oral) targeting cannabis-induced CNS effects; thus aligns with Oral Small Molecule Therapeutics.
|
$94.08M |
$2.20
-3.93%
|
|
RPTX
Repare Therapeutics Inc.
RP-1664 is an oral small-molecule PLK4 inhibitor, indicating a major product category of oral small-molecule therapeutics.
|
$91.93M |
$2.18
+1.87%
|
|
FBIO
Fortress Biotech, Inc.
Emrosi is a modified-release oral antibiotic (minocycline), placing Fortress in the Oral Small Molecule Therapeutics category via its portfolio.
|
$87.18M |
$3.35
+14.16%
|
|
ACOG
Alpha Cognition Inc. Common Stock
ZUNVEYL is an oral small molecule therapeutic for Alzheimer's disease.
|
$85.81M |
$5.06
-4.71%
|
|
BYSI
BeyondSpring Inc.
Plinabulin is a small-molecule therapeutic; categorize under Oral Small Molecule Therapeutics.
|
$85.10M |
$1.98
-6.16%
|
|
BMEA
Biomea Fusion, Inc.
Direct product category: Biomea Fusion is developing oral small molecule therapeutics, including icovamenib and BMF-650.
|
$83.91M |
$1.34
-4.61%
|
|
ALGS
Aligos Therapeutics, Inc.
Aligos develops oral small-molecule therapeutics across its pipeline (HBV CAM-E, THR-β agonist, and pan-coronavirus protease inhibitor).
|
$81.78M |
$12.22
-8.09%
|
|
ANVS
Annovis Bio, Inc.
Buntanetap is described as an orally administered small molecule therapeutic, aligning with the 'Oral Small Molecule Therapeutics' investable theme.
|
$80.48M |
$4.17
+10.16%
|
|
ACRV
Acrivon Therapeutics, Inc. Common Stock
Oral Small Molecule Therapeutics: ACR-368 and ACR-2316 are oral small-molecule inhibitors (CHK1/CHK2 and WEE1/PKMYT1).
|
$79.58M |
$2.56
+1.19%
|
|
CRVO
CervoMed Inc.
Neflamapimod is an orally administered, small-molecule therapeutic, aligning with the 'Oral Small Molecule Therapeutics' category.
|
$78.19M |
$8.45
-0.06%
|
|
EQ
Equillium, Inc.
EQ302 is described as an oral, bispecific inhibitor, fitting the Oral Small Molecule Therapeutics category.
|
$76.16M |
$1.20
-6.64%
|
|
CRDL
Cardiol Therapeutics Inc.
CardiolRx is an oral small-molecule therapeutic.
|
$75.81M |
$1.03
-4.17%
|
|
MNOV
MediciNova, Inc.
MN-166 (ibudilast) and MN-001 (tipelukast) are oral small-molecule therapeutics in MediciNova's development pipeline.
|
$75.53M |
$1.52
-0.97%
|
|
PLRX
Pliant Therapeutics, Inc.
Company's lead and mid-stage assets include oral small-molecule therapeutics (bexotegrast and PLN-101095) targeting integrin pathways.
|
$75.51M |
$1.26
+2.85%
|
|
ASRT
Assertio Holdings, Inc.
Sympazan is an oral small-molecule therapeutic delivered as a film, fitting the Oral Small Molecule Therapeutics category.
|
$73.32M |
$0.74
-3.36%
|
|
CLNN
Clene Inc.
CNM-Au8 is the lead asset pursued as a therapeutic, likely administered orally as a small-molecule/low-molecular-weight product.
|
$72.13M |
$7.22
|
|
IFRX
InflaRx N.V.
INF904 is an oral small-molecule C5aR antagonist, representing a major Oral Small Molecule Therapeutics program.
|
$61.83M |
$1.01
-3.33%
|
|
IMUX
Immunic, Inc.
Immunic's lead programs are oral, small-molecule therapeutics (e.g., vidofludimus calcium and IMU-856).
|
$61.31M |
$0.64
+3.22%
|
|
KPTI
Karyopharm Therapeutics Inc.
Selinexor is an oral small molecule therapeutic; the company emphasizes oral regimens and late-stage oral therapies in MF and EC, constituting a major product category.
|
$60.27M |
$6.82
-1.87%
|
|
DRRX
DURECT Corporation
Larsucosterol is described as an orally bioavailable small molecule therapeutic and the lead program for DURECT, targeting alcohol-associated hepatitis.
|
$59.29M |
$1.91
|
|
KRON
Kronos Bio, Inc.
The company's lead assets are small-molecule therapeutics (e.g., istisociclib), indicating a focus on Oral Small Molecule Therapeutics.
|
$53.65M |
$0.88
|
|
ANL
Adlai Nortye Ltd.
The company’s pipeline includes oral small-molecule therapeutics (e.g., AN4005, AN9025), aligning with the Oral Small Molecule Therapeutics category.
|
$50.87M |
$1.46
+5.80%
|
|
TELO
Telomir Pharmaceuticals, Inc. Common Stock
Telomir-1 is described as an oral small molecule therapeutic candidate, directly matching the 'Oral Small Molecule Therapeutics' tag.
|
$46.81M |
$1.44
-1.03%
|
|
GRCE
Grace Therapeutics, Inc.
GTx-102.00 is a betamethasone oral-mucosal spray, representing an oral small-molecule therapeutic asset.
|
$45.77M |
$3.27
-1.06%
|
|
XFOR
X4 Pharmaceuticals, Inc.
Mavorixafor is an oral small-molecule therapeutic agent.
|
$44.61M |
$3.88
-0.77%
|
|
NRXP
NRx Pharmaceuticals, Inc.
NRX-101 is an oral small-molecule therapeutic (D-cycloserine + lurasidone) for bipolar depression.
|
$39.02M |
$2.00
-3.38%
|
|
JUNS
Jupiter Neurosciences, Inc.
Direct product category: orally administered small-molecule therapeutics based on a resveratrol platform (JOTROL).
|
$39.01M |
$1.09
-2.68%
|
|
LTRN
Lantern Pharma Inc.
LP-300, LP-184, LP-284 are small-molecule oncology therapeutics candidates, aligning with the oral small molecule therapeutics category.
|
$38.88M |
$3.51
-2.50%
|
|
CPIX
Cumberland Pharmaceuticals Inc.
Ifetroban is a small-molecule therapeutic candidate, categorized as an oral small-molecule therapeutic if applicable.
|
$37.85M |
$3.01
+18.97%
|
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