Adial Pharmaceuticals Granted New U.S. Patent Expanding Genetic-Based Treatment for Alcohol and Opioid Disorders

ADIL
October 05, 2025

Adial Pharmaceuticals announced on February 19, 2025, that the United States Patent and Trademark Office (USPTO) issued patent number 12,226,401 on February 18, 2025. This patent expands coverage of Adial’s genetic-based approach to treating and diagnosing alcohol use disorder and other drug dependencies.

The new patent covers claims focusing on a method for identifying genetic markers in patients with alcohol or opioid-related disorders. Specifically, it includes the AC genotype of rs17614942 in the HTR3B gene and the AG genotype of rs1150226 in the HTR3A gene.

This expansion allows providers to offer tailored treatment plans using AD04 based on a patient’s unique genetic profile. This personalized method is designed to deliver optimal outcomes and reduce risks associated with one-size-fits-all approaches, enhancing effectiveness for millions suffering from addiction.

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