AstraZeneca Expands Liquid‑Biopsy Access Partnership to China

AZN
December 08, 2025

AstraZeneca and Pillar Biosciences have extended their laboratory‑access program for next‑generation sequencing‑based liquid‑biopsy tumor profiling to include China, creating a new channel for rapid, affordable, and kit‑based NGS testing in local hospitals and community laboratories.

The expansion is driven by China’s large cancer burden—approximately 24 % of new global cancer cases and 30 % of cancer‑related deaths, according to WHO’s GLOBOCAN 2022 report—and the country’s growing demand for precision‑medicine diagnostics. Lung, colorectal, and liver cancers are the most prevalent in China, and early detection and molecular profiling remain limited in many regions.

The tripartite agreement adds Shanghai Zhengu Biological Technology Co., Ltd. (Zhengu) as a key partner. Zhengu will support assay validation and help implement Pillar’s liquid‑biopsy panels in Chinese hospital laboratories, ensuring that the panels meet local regulatory and quality standards and can be deployed at scale.

AstraZeneca’s oncology platform benefits from the partnership by integrating advanced genomic profiling into its antibody‑drug conjugate (ADC) and targeted‑therapy pipelines. The company sees the expanded access as a way to generate actionable biomarker data that can inform treatment decisions and accelerate the development of new ADCs and targeted agents in China.

While the announcement does not disclose immediate revenue figures, the expansion is expected to strengthen AstraZeneca’s commercial footprint in China and support its broader strategy of deepening oncology diagnostics capabilities worldwide. The company’s management highlighted that the partnership will help address the high cancer burden in China by improving early detection and precision diagnostics, thereby expanding access to targeted therapies.

The move also positions AstraZeneca to capture a share of China’s rapidly expanding liquid‑biopsy market, which is projected to grow as the country invests in precision‑medicine infrastructure and as regulatory pathways for liquid‑biopsy assays become more streamlined.

The partnership underscores AstraZeneca’s commitment to precision oncology and its strategy of leveraging diagnostic data to accelerate drug development and improve patient outcomes in key growth markets.

The expansion is a strategic milestone that aligns with AstraZeneca’s long‑term focus on precision medicine, and it is likely to influence the company’s future pipeline development and market positioning in China.

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