Compugen Secures New U.S. Patent for COM902 Triple Combination Therapy

CGEN
November 01, 2025

Compugen Ltd. announced on November 27, 2024, that the United States Patent and Trademark Office (USPTO) granted U.S. Patent No. 12152084, titled 'Triple combination antibody therapies'. This patent covers the method of use for COM902, the company's reduced Fc anti-TIGIT antibody, and additional TIGIT backup antibodies.

The patent specifically protects the use of COM902 in a triple combination with any anti-PD-1 antibody and any anti-PVRIG antibody for the treatment of cancer. This expands Compugen's existing intellectual property, safeguarding its innovative approach to cancer immunotherapy.

The new patent is expected to expire no earlier than August 2037 in the United States, providing long-term protection for this strategic combination. This intellectual property expansion is a crucial part of Compugen's strategy to deliver innovative treatments and create shareholder value.

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