FlyteHealth announced a new direct‑to‑employer pathway that will allow self‑insured organizations to provide employees with Eli Lilly’s obesity medications, including Mounjaro and Zepbound, beginning in early 2026. The partnership leverages FlyteHealth’s AI‑driven, outcomes‑focused care platform to bundle medication access with behavioral support and real‑time adherence monitoring.
The pathway offers a bundled pricing model that bypasses traditional pharmacy benefit managers, giving employers a predictable cost structure and a single point of contact for medication management. FlyteHealth’s platform integrates with employers’ benefits systems, automatically enrolling eligible employees, tracking prescription fill rates, and providing coaching to improve weight‑loss outcomes. The integration also feeds data back to Lilly, enabling the company to monitor real‑world effectiveness and adjust pricing or support programs accordingly.
By expanding beyond PBM channels, Lilly can increase prescription volume and capture a larger share of the rapidly growing obesity‑drug market. The direct‑to‑employer model addresses a key employer pain point—high cost and complex access—while positioning Lilly as a value‑based partner that ties reimbursement to patient outcomes. This strategy aligns with Lilly’s broader goal of scaling its GLP‑1 portfolio and securing long‑term revenue streams.
FlyteHealth’s cardiometabolic expertise gives the partnership a competitive edge over similar initiatives, such as Novo Nordisk’s collaboration with Waltz Health. While both companies offer direct‑to‑employer access, FlyteHealth’s focus on integrated care and AI‑guided treatment plans provides a more comprehensive solution for weight management, potentially improving adherence and clinical results compared with models that rely solely on medication distribution.
Eli Lilly’s financial performance underscores the strategic importance of this expansion. In Q3 2025, the company reported a 54% year‑over‑year revenue increase to $17.60 billion, driven largely by Mounjaro and Zepbound sales. Management raised its full‑year revenue guidance to $63.0 billion–$63.5 billion, citing sustained demand and the launch of new indications. CEO David A. Ricks highlighted the “strong uptake” of the obesity drugs and the company’s commitment to scaling manufacturing capacity to meet demand. EVP of Lilly USA, Ilya Yuffa, emphasized that the direct‑to‑employer model “provides clarity on medicine costs and flexibility for employers to design benefit plans that fit their workforce.”
The partnership represents a strategic pivot that could accelerate Lilly’s market penetration, enhance its value‑based care portfolio, and strengthen its competitive position against rivals in the GLP‑1 space. By aligning distribution, care, and outcomes, FlyteHealth and Lilly aim to deliver a more efficient, cost‑effective solution for employers and patients alike.
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