Microsoft, Google, Amazon Join U.S. Energy Department in Genesis Mission to Accelerate AI‑Driven Scientific Research

MSFT
December 19, 2025

Microsoft, Google, and Amazon have joined the U.S. Department of Energy’s Genesis Mission, a national initiative that seeks to harness artificial intelligence to accelerate scientific discovery and energy‑related research.

The partnership will combine Microsoft’s Azure supercomputing and AI services, Google Cloud’s Vertex AI and data‑analytics tools, and Amazon Web Services’ SageMaker and high‑performance computing infrastructure. Together, the three firms will provide a unified platform that connects DOE’s national laboratories, supercomputers, experimental facilities, and data sets, enabling researchers to train large‑scale models, run complex simulations, and generate predictive insights across energy, manufacturing, and drug discovery domains.

Genesis Mission’s overarching goal is to double the productivity and impact of U.S. research and development within a decade. The program will deploy an integrated AI ecosystem that links supercomputers, AI systems, and experimental facilities, with a target to deliver breakthrough results in energy efficiency, materials science, and climate modeling by 2035. DOE has earmarked more than $320 million for AI infrastructure and expects the partnership to accelerate the development of new models and tools that can be deployed across its laboratories.

From a business perspective, the collaboration positions Microsoft, Google, and Amazon as the primary AI cloud providers for federal research. The partnership opens pathways to future government contracts and grants, while reinforcing each company’s strategic focus on public‑sector AI services. The alliance also signals to the broader market that the tech giants are committed to supporting national research priorities, potentially strengthening their competitive edge over rivals that are not involved in the initiative.

The Genesis Mission is anchored in President Trump’s Executive Order on removing barriers to American leadership in artificial intelligence and the broader America’s AI Action Plan. DOE’s investment and the public‑private partnership reflect a national strategy to reduce reliance on foreign AI capabilities and to accelerate domestic innovation. The collaboration builds on prior engagements, such as Microsoft’s five‑year AI‑cloud agreement with the UK government and Google’s long‑standing work with DOE on high‑performance computing projects.

Dr. Darío Gil, DOE Under Secretary for Science and Genesis Mission Director, said the partnership will “dramatically increase the productivity of American scientists and researchers.” Michael Kratsios, Director of the White House Office of Science and Technology Policy, added that the announcement of 24 new research partnerships is “only the beginning” of a broader effort to bring the entire scientific community into the Genesis Mission.”

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