Oragenics Announces Strategic Partnership with BRAINBox Solutions to Revolutionize Concussion Care

OGEN
October 05, 2025

Oragenics, Inc. announced on February 11, 2025, a strategic partnership with BRAINBox Solutions, a leader in multi-modality diagnostics for traumatic brain injury (TBI). This collaboration aims to develop a comprehensive 'trigger-to-treat' platform for mild traumatic brain injury (mTBI), also known as concussion.

The partnership intends to integrate BRAINBox’s proprietary diagnostic product platform, which uses neurological biomarkers, neuropsychological assessments, and AI-driven analytics, with Oragenics’ intranasal therapeutic candidate, ONP-002. This integration seeks to provide rapid diagnosis, predictive prognosis, and timely, targeted treatment for concussion patients.

Interim CEO Janet Huffman stated that combining their innovative intranasal therapeutic with BRAINBox’s diagnostic platform could offer a comprehensive solution for both identification and treatment of mTBI. This collaboration is expected to be instrumental in Oragenics' upcoming Phase IIa trials, enabling precise patient selection and real-time monitoring of therapeutic efficacy.

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