Oramed Terminates Joint Venture with HTIT, Announces Independent Path for Oral Insulin Program

ORMP
October 23, 2025

On October 23, 2025, Oramed Pharmaceuticals Inc. issued a letter to shareholders announcing the termination of its joint venture with Hefei Tianhui Biotech Co. Ltd. (HTIT). The termination was triggered by HTIT’s inability to satisfy the closing financial conditions required under the joint venture agreement.

With the joint venture dissolved, Oramed will now pursue its refined oral insulin program independently. The company stated it will maintain full control over the development of ORMD‑0801 and will seek alternative manufacturing arrangements to advance the program in the United States.

The letter also highlighted Oramed’s diversified investment portfolio, noting continued appreciation in its holdings of Scilex, Alpha Tau Medical, and other assets. However, the termination of the HTIT partnership marks a significant strategic shift, as the company moves away from a joint venture model toward an in‑house development path for its core oral insulin technology.

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