Polyrizon Signs LOI to Develop Intranasal Psychedelic-Based Treatments

PLRZ
October 04, 2025

Polyrizon Ltd. announced today the signing of a non-binding Letter of Intent (LOI) with a biotech company specializing in psychedelic-derived therapeutics. The agreement aims to develop a novel intranasal formulation for psychedelic-based treatment applications.

This collaboration seeks to leverage Polyrizon’s proprietary platform to optimize the delivery of innovative psychedelic treatments, potentially enhancing bioavailability, efficacy, and patient accessibility. Polyrizon will lead the formulation's development, utilizing its mucoadhesive drug delivery technology.

Under the terms of the LOI, the psychedelic company will fund the research and development process, including feasibility studies. If successful, the companies intend to negotiate a definitive agreement, with Polyrizon slated to receive royalty payments for any future commercialization of the product.

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