Plus Therapeutics Renews Strategic Agreement for Rhenium-186 Radioisotope Supply

PSTV
October 05, 2025

Plus Therapeutics, Inc. announced on December 3, 2024, the renewal of its Master Services Agreement (MSA) with Telix IsoTherapeutics Group Inc. This agreement secures a reliable supply of cGMP Re-186, the radioisotope used in Plus Therapeutics’ lead radiotherapeutic candidate Rhenium (186Re) Obisbemeda.

This continuing agreement builds on the company's comprehensive supply chain strategy, which also includes a partnership with SpectronRx for final drug manufacturing. The goal is to establish a scalable, end-to-end supply chain.

Securing the supply of Re-186 is crucial for meeting the demands of late-stage clinical trials and future commercial needs. The agreement also includes the production of aluminum perrhenate, a key radionuclide intermediate, and final processing of cGMP Re-186.

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