Provectus Biopharmaceuticals Announces Publication of Moffitt Cancer Center Research on PV-10 for Head and Neck Cancer

PVCT
October 07, 2025

Provectus Biopharmaceuticals, Inc. announced the publication of preclinical research by Christine Chung, MD, and her team at Moffitt Cancer Center. The study, published in Molecular Cancer Therapeutics, evaluated intratumoral PV-10 in models of head and neck squamous cell carcinoma (HNSCC).

The research highlights novel mechanistic findings, specifically PV-10's ability to induce immunogenic cell death in HNSCC. This scientific validation adds to the understanding of PV-10's effects and supports its broad immunotherapy platform.

Dominic Rodrigues, President and Vice Chair of the Board of Directors of Provectus, stated that these results align with the company's strategy, including a planned Phase 1 trial of intratumoral PV-10 in pre-operative penile squamous cell carcinoma at Moffitt, potentially later this year. The publication provides a strong scientific foundation for further clinical development of PV-10.

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