Pyxis Oncology's PYX-201 Granted FDA Fast Track Designation for Head and Neck Cancer

PYXS
October 07, 2025

Pyxis Oncology, Inc. announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track Designation to PYX-201. This designation is for the treatment of adult patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) whose disease has progressed following treatment with platinum-based chemotherapy and an anti-PD-(L)1 antibody.

Fast Track designation is an FDA program designed to facilitate and expedite the development and review of new drugs for serious or life-threatening conditions. To qualify, a drug must demonstrate the potential to address an unmet medical need in the designated condition.

This designation acknowledges the significant medical need in R/M HNSCC, a condition where almost 50% of cases progress to recurrent or metastatic cancer post-initial treatment, leading to a median overall survival of less than a year. The company anticipates this will help accelerate the development of PYX-201.

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