QIAGEN and Incyte Announce Precision Medicine Collaboration for MPN Companion Diagnostics

QGEN
October 08, 2025

QIAGEN N.V. and Incyte announced a new global collaboration on June 17, 2025, to develop a novel diagnostic panel. This panel will support Incyte’s investigational therapies for patients with myeloproliferative neoplasms (MPNs), a group of rare blood cancers, including Incyte’s monoclonal antibody INCA033989 targeting mutant calreticulin (mutCALR).

Under the Master Collaboration Agreement, QIAGEN will develop a multimodal panel using next-generation sequencing (NGS) technology for detecting clinically relevant gene alterations in hematological malignancies. The panel will be validated on the Illumina NextSeq 550Dx platform, leveraging QIAGEN’s partnership with Illumina.

QIAGEN will also support regulatory submission processes and market access activities across the United States, European Union, and Asia-Pacific regions. This partnership strengthens QIAGEN’s role in offering companion diagnostics for the growing number of biomarkers in onco-hematology, aiming to improve patient outcomes through personalized treatment decisions.

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