Regeneron announced that a bispecific antibody combination therapy achieved complete disease disappearance in a subset of previously untreated patients enrolled in a phase 2 trial for a blood cancer. The trial, which evaluated the therapy’s efficacy and safety, reported that several patients achieved complete remission as assessed by standard imaging and biomarker criteria.
The study, conducted under a clinical trial identifier that has not been publicly disclosed, was presented at the European Society for Medical Oncology (ESMO) meeting in October 2025 and confirmed in a company announcement on December 6 2025. The early clinical success indicates that the therapy can eradicate disease in patients who have not yet received treatment, a result that could shorten the development timeline and bring the product closer to regulatory approval.
This milestone is significant for Regeneron’s oncology pipeline, which is heavily focused on bispecific antibodies for hematologic malignancies. A complete remission in untreated patients demonstrates strong efficacy and may accelerate the company’s ability to bring a new therapy to market, thereby enhancing its competitive position in the blood‑cancer segment and potentially expanding future revenue streams.
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