Savara Announces Over 50% Increase in Estimated U.S. Autoimmune PAP Patient Population

SVRA
October 05, 2025

Savara Inc. announced a new U.S. health claims data analysis indicating an approximately 50% larger estimated autoimmune pulmonary alveolar proteinosis (aPAP) patient population than previously reported. The updated estimate identifies around 5,500 aPAP patients in the U.S., compared to the prior estimate of approximately 3,600 patients from 2023.

This revised estimate suggests a significantly expanded potential market for MOLBREEVI, Savara's lead product candidate for aPAP. A larger addressable patient population can enhance the commercial prospects and long-term revenue potential of the therapy, pending regulatory approval.

The new analysis provides a more comprehensive understanding of the prevalence of aPAP in the United States. This information is crucial for commercial planning and market penetration strategies for MOLBREEVI.

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