Waystar Holding Corp. announced the launch of an agentic artificial‑intelligence capability that expands its AltitudeAI suite and is designed to operate autonomously within provider workflows, executing tasks and learning from outcomes with minimal human intervention.
The new AI leverages Waystar’s proprietary data network, which processes more than 7.5 billion transactions annually and includes data from one in three U.S. hospital discharges. By analyzing full medical records and prioritizing roughly 30,000 relevant data points, the system automatically pre‑populates correction requests and has already cut manual correction workload by about 40%, freeing clinicians to focus on higher‑value care and helping to mitigate nurse burnout amid staffing shortages.
Waystar’s existing AI engine has already prevented $15.5 billion in denials over the past year, and the agentic extension is expected to further streamline revenue‑cycle operations, reduce administrative costs, and improve provider reimbursement accuracy. The technology is a key component of the company’s vision for a fully autonomous revenue‑cycle platform that continuously learns and improves in real time.
The launch follows a strong Q3 2025 earnings report in which Waystar generated $268.7 million in revenue—up 12% year‑over‑year—while maintaining an adjusted EBITDA margin of 42%. The company also raised its full‑year 2025 revenue and adjusted EBITDA guidance, and it recently closed the acquisition of Iodine Software to accelerate AI‑powered platform development.
Investors reacted negatively to the announcement, citing heightened competition from Anthropic’s newly unveiled healthcare AI tools. Despite the short‑term market pressure, management remains confident in Waystar’s competitive moat, driven by its extensive data network and proven AI track record.
CEO Matt Hawkins said, “With that momentum, agentic AI built on an unparalleled proprietary dataset accelerates our vision for the industry’s first autonomous revenue‑cycle platform and advances our mission to simplify healthcare payments for providers and their patients.”
Waystar’s agentic AI launch positions the company to deepen its competitive moat, drive broader adoption of its AI‑powered solutions across the healthcare payment ecosystem, and continue to innovate in the rapidly evolving AI‑driven revenue‑cycle market.
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