Xtant Medical Launches CollagenX, Expanding Its Orthobiologics Portfolio

XTNT
November 05, 2025

Xtant Medical introduced CollagenX on November 5 2025, a bovine collagen particulate product designed for surgical wound closure. The launch adds a new, high‑margin option to the company’s orthobiologics lineup and is intended to be used in any surgical procedure that currently falls under Xtant’s orthobiologics umbrella.

CollagenX is engineered to provide consistent, high‑quality collagen particles, a capability that stems from Xtant’s vertically integrated manufacturing plant in Montana. The company’s control over the entire production chain—from raw‑material sourcing to final product sterilization—helps maintain product quality and can translate into higher profit margins compared with competitors that rely on third‑party suppliers.

The product launch fits squarely within Xtant’s broader strategy to broaden its biologics portfolio and strengthen its competitive moat. President and CEO Sean Browne emphasized that “the commercial launch of CollagenX for surgical wound closure enhances our extensive orthobiologics portfolio and demonstrates our dedication to innovation in meeting the diverse needs of surgeons and patients. As one of the few fully vertically integrated regenerative medicine firms, we are uniquely equipped to deliver the quality and consistency that can significantly improve patient outcomes.”

Xtant’s recent financial performance underscores the significance of the launch. In Q2 2025, the company reported revenue of $35.4 million—$4.05 million above the $31.35 million consensus forecast—and a net income of $3.6 million, a turnaround from a $3.9 million loss in the same quarter a year earlier. Gross margin expanded to 68.6% from 62.1% in the prior year, and adjusted EBITDA rose to $6.9 million from a $0.6 million loss in Q2 2024. In light of these results, Xtant raised its full‑year 2025 revenue guidance to $131–$135 million, reflecting confidence in continued demand for its orthobiologics products.

The orthobiologics market represents a $2.5 billion domestic opportunity, with adjacent markets potentially exceeding $10 billion. CollagenX targets the surgical wound‑closure segment, a niche that can capture a share of this broader market. While specific market‑size estimates for CollagenX are not publicly disclosed, the company’s strategy to diversify into wound closure aligns with the growing demand for regenerative solutions in surgical settings.

CollagenX competes with other bovine collagen particulate products, but Xtant’s vertical integration provides a competitive edge. The company’s Montana facility not only ensures consistent product quality but also offers scalable manufacturing capacity, positioning Xtant to meet potential demand surges without compromising on quality or cost efficiency.

The launch of CollagenX signals Xtant’s continued focus on high‑margin orthobiologics and its commitment to expanding its OEM supply base. By adding a new, versatile wound‑closure product, the company is poised to capture additional revenue streams and reinforce its position as a diversified regenerative‑medicine supplier.

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